Uma Thurman is joining fashion forces with Saks Fifth Avenue and Donna Karan to help in the battle against breast cancer. The actress was named Friday as the ambassador for Saks’ Annual Key to the Cure shopping event, which in partnership with the Breast Cancer Research Foundation, has raised more than $33 million for cancer research in the 12 years since its inception. “Everyone I know has been affected by breast cancer one way or the other,” says Thurman in a release. “It is vital that we work toward a cure as well as develop more accurate and advance testing.” Thurman will star in print ads as well as a national public service announcement sporting a limited-edition and very chic T-shirt designed by Donna Karan. One hundred percent of the proceeds from the $35-shirt will be donated to local partner charities. “For me, it’s not just about dressing women; it’s about addressing the issues that are so important to all of us,” says Karan in a release. The T-shirts will be available at all Saks Fifth Avenue stores and on Saks.com beginning October 1.